Pharmacogenetics and mental disease

Pharmacogenetics, pharmacogenomics and airway disease

The availability of a draft sequence for the human genome will revolutionise research into airway disease. This review deals with two of the most important areas impinging on the treatment of patients: pharmacogenetics and pharmacogenomics. Considerable inter-individual variation exists at the DNA level in targets for medication, and variability in response to treatment may, in part, be determi...

Pharmacogenetics and the treatment of cardiovascular disease.

Mechanisms linking Mental Health Problems and Cardiac Disease: A Review

Psychological problems play a critical role in development of cardiovascular disease. Several mechanisms were suggested to explain the association and mechanism of this effect, recently. Knowledge of the mechanisms mediating the association between psychological status and heart disease could help in developing treatments. The effects of mind and mood on the cardiovascular system can be due to ...

Pharmacogenetics and cardiovascular disease--implications for personalized medicine.

The past decade has seen tremendous advances in our understanding of the genetic factors influencing response to a variety of drugs, including those targeted at treatment of cardiovascular diseases. In the case of clopidogrel, warfarin, and statins, the literature has become sufficiently strong that guidelines are now available describing the use of genetic information to guide treatment with t...

U.S.S.R. and Mental Disease